Dead 2.0 has a funny bit on a horrendously badly named Web 2.0 startup: Smartpox:

It actually sounds like a more advanced version of smallpox! 

…

Avoid naming your company after a deadly disease.  This also means budding entrepreneurs probably don’t want to start…

AIDSter
EbolaCrunch
GigaMumps
Hepatitr
SyphiliBox
AllMalariaNet

Leaving aside the questions about Smartpox’s business model , which seem legit, look at the CNET article by Michael Kanellos that Dead references, which offers up 5 things not to do when naming your company, and 3 hints to consider (summarized…who likes reading long things anyway?):

1. When in doubt, go medieval. If you can fit your company name into this sentence: “What (your name here) is but a boy. I will smote him in one blow,” then you have chosen well. Ceragon Networks is a great example.

Weapons also work. Crossbow Technologies. This technique was successful for my old college roommate. He had a company named LightHammer. He picked the name because it both evoked “The Lord of the Rings” and “Hammer of the Gods” (the Led Zeppelin biography). He sold it to SAP.

2. Things that sound like a Spanish restaurant. Spansion. Taleo. Digitas.

3. If it sounds like someone that William Shatner would wrestle, you’re all set. Santarus. Sirtris. DayStar. Questcor Pharmaceuticals.

But back to Smartpox – just saying that makes me feel like I need to grab some antibiotics, or get a really ugly series of shots. I predict a rebrand if the company makes it out of the gate.